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Combination of G-CSF and a TLR4 inhibitor reduce inflammation and promote regeneration in a mouse model of ACLF
Acute-on-chronic liver failure is associated with severe liver inflammation and poor short-term survival. Therefore, effective treatments are urgen...
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CGT 4.0: a distant dream or inevitable future? Smart process automation is critical to make efficient scalability of CGT manufacturing a reality
Collaboratively developed by the PAT4CGT consortium, the article describes what we believe are the three layers needed to bring Industry 4.0 to Cel...
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Watch the First CGT Helix Event
On 18 June 2024, project PAT4CGT delivered its first online CGT Helix event "Collaborative Frontiers: Advancing CGT Manufacturing Technologies". W...
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Chemotherapy Device for Imatinib Drug Monitoring
Background - The effectiveness of many anticancer drugs varies greatly from patient to patient, with risks of incorrect dosages and adverse side ef...
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Anti-Cancer Efficient and Non-Toxic Palladium Compounds
Background - Platinum-based antineoplastic drugs have been used since the late 1970s, although they sometimes show significant nephro- and neurotox...
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Bicyclic Peptide Inhibitors of the Human Urokinase-Type Plasminogen Activator (HUPA)
Background - Bicyclic peptides are small polypeptides that exhibit properties typical of both monoclonal antibodies (high target specificity and af...
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Dynamics of a "Healthy" Viable Microbiome to Prevent Diseases
Background - Research at Ca Foscari Venice University is focused on understanding what constitutes a “healthy” microbiome in terms of composition,...
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Reversible Monoacylglycerol Lipase (MAGL) Inhibitors for Neurodegenerative Pathologies and Tumour Treatment
Background - The enzyme monoacylglycerol lipase (MAGL), which is part of the endocannabinoid system (ECS), has therapeutic potential for the treatm...
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Less Toxic Chemotherapy with Palladium
Background - Targeted, efficient and non-toxic anti-cancer drugs: a new class of palladium compounds could be used as innovative chemotherapeutic m...
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Copper Compounds for the Treatment of Ovarian Cancer
Background - The present invention is a nanomaterial containing a pharmaceutical composition based on copper (II) nitroprusside (CuNP) for use in...